Lupus -causes, Symptoms, Treatment

There are couple main forms of this autoimmune disease - Systemic lupus erythematosus and Discoid lupus erythematosus.

Systematic lupus erythematosus (SLE) is the most common and debilitating form which can purpose conflagration of the joints, tendons, connective tissue and major organs such as the kidneys and heart. However, the most obvious token is a butterfly-shaped incautious which occurs across the cheeks and nose.

Causes of Lupus

It's generally believed that lupus is caused by alterations in the immune system. The body's immune system normally fights foreign bacteria and viruses; notwithstanding, with lupus, the immune system may fail to recognize "self" substances and will make antibodies that have a cut at the body's own tissue. This is called autoimmunity. The body may also fail to clear antigens (from abroad particles), and certain white blood cells may behave abnormally.

Genetics

Most researchers feel that it is credible that there is a genetic component to lupus. The condition can have being considered hereditary in that people who have a family history or lupus itself, other autoimmune condtions, or allergic conditions, strike one as being to be at increased risk of developing the ail. This is not to say that everyone with a family history such as this direct cause to grow lupus. Researchers have not discovered a single gene that is linked to lupus but have found groups of genes, particularly on chromosomes 6, 16 and 20, which appear to be to indicate a person is at greater risk of developing the condition.

Symptoms of Lupus

SLE symptoms may develop slowly over months or years, or they may appear suddenly. Symptoms tend to be worse during winter months, perhaps because prolonged exposure to sunlight in the summer causes a gradual build-up of factors that trigger symptoms months later.

Each person with lupus has scornfully diverse symptoms that can range from mild to sedate and may come and go over measure. However, some of the in the greatest degree hackneyed symptoms of lupus embrace painful or swollen joints (arthritis), unexplained fever, and highest fatigue. A characteristic red skin thoughtless (the so-called butterfly or malar indiscreet) may be manifest across the nose and cheeks. Affecting what the Lupus Foundation of America estimates is 500,000 to 1.5 the multitude Americans, lupus is a chronic inflammatory disease that affects various parts of the body, especially the skin, joints, high birth, and kidneys

Lupus treated

Steroids. Steroid creams can be applied immediately to rashes. The use of creams is usually safe and effective, especially for mild rashes. The use of steroid creams or tablets in low doses be able to be potent for mild or moderate features of lupus. Steroids also can be used in higher doses when inward organs are threatened. Unfortunately, high doses also are most likely to produce side furniture.

Plaquenil (hydroxychloroquine)—Commonly used to helper restrain mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares.

antimalarial drugs similar as chloroquine phosphate or hydroxychloroquine for rashes, arthritis and malaise

immunosuppressive and cytotoxic drugs such as Immuran (azathioprine) and Cytoxan (cycyclophosphamide) are prescribed with vital organs are involved and/or corticosteroids aren'cheek by jowl operative.

Source: http://www.articlesbase.com/diseases-and-conditions-articles/lupus-causes-symptoms-treatment-461412.html

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June 27th, 2008 - Posted in conditions | |

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